Mapping of Dynamic Transcriptome Changes Associated With Silica-Triggered Autoimmune Pathogenesis in the Lupus-Prone NZBWF1 Mouse

Crystalline silica (cSiO(2)) is a widely recognized environmental trigger of autoimmune disease. In the lupus-prone female NZBWF1 mouse, airway exposure to cSiO(2) triggers pulmonary ectopic lymphoid neogenesis, systemic autoantibody elevation, and glomerulonephritis. Here we tested the hypothesis t...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Bates, Melissa A., Benninghoff, Abby D., Gilley, Kristen N., Holian, Andrij, Harkema, Jack R., Pestka, James J.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450439/
https://ncbi.nlm.nih.gov/pubmed/30984195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00632
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