Silica Triggers Inflammation and Ectopic Lymphoid Neogenesis in the Lungs in Parallel with Accelerated Onset of Systemic Autoimmunity and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse

Genetic predisposition and environmental factors influence the development of human autoimmune disease. Occupational exposure to crystalline silica (cSiO(2)) has been etiologically linked to increased incidence of autoimmunity, including systemic lupus erythematosus (SLE), but the underlying mechani...

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Foilsithe in:PLoS One
Main Authors: Bates, Melissa A., Brandenberger, Christina, Langohr, Ingeborg, Kumagai, Kazuyoshi, Harkema, Jack R., Holian, Andrij, Pestka, James J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433215/
https://ncbi.nlm.nih.gov/pubmed/25978333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125481
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