Silica Triggers Inflammation and Ectopic Lymphoid Neogenesis in the Lungs in Parallel with Accelerated Onset of Systemic Autoimmunity and Glomerulonephritis in the Lupus-Prone NZBWF1 Mouse

Genetic predisposition and environmental factors influence the development of human autoimmune disease. Occupational exposure to crystalline silica (cSiO(2)) has been etiologically linked to increased incidence of autoimmunity, including systemic lupus erythematosus (SLE), but the underlying mechani...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bates, Melissa A., Brandenberger, Christina, Langohr, Ingeborg, Kumagai, Kazuyoshi, Harkema, Jack R., Holian, Andrij, Pestka, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433215/
https://ncbi.nlm.nih.gov/pubmed/25978333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125481
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