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Altered connectivity in depression: GABA and glutamate neurotransmitter deficits and reversal by novel treatments

The mechanisms underlying the pathophysiology and treatment of depression and stress-related disorders remain unclear, but studies in depressed patients and rodent models are beginning to yield promising insights. These studies demonstrate that depression and chronic stress exposure cause atrophy of...

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Publicado en:Neuron
Autores principales: Duman, Ronald S., Sanacora, Gerard, Krystal, John H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450409/
https://ncbi.nlm.nih.gov/pubmed/30946828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.03.013
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