Broad Hemagglutinin-Specific Memory B Cell Expansion by Seasonal Influenza Virus Infection Reflects Early-Life Imprinting and Adaptation to the Infecting Virus

Memory B cells (MBCs) are key determinants of the B cell response to influenza virus infection and vaccination, but the effect of different forms of influenza antigen exposure on MBC populations has received little attention. We analyzed peripheral blood mononuclear cells and plasma collected follow...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tesini, Brenda L., Kanagaiah, Preshetha, Wang, Jiong, Hahn, Megan, Halliley, Jessica L., Chaves, Francisco A., Nguyen, Phuong Q. T., Nogales, Aitor, DeDiego, Marta L., Anderson, Christopher S., Ellebedy, Ali H., Strohmeier, Shirin, Krammer, Florian, Yang, Hongmei, Bandyopadhyay, Sanjukta, Ahmed, Rafi, Treanor, John J., Martinez-Sobrido, Luis, Golding, Hana, Khurana, Surender, Zand, Martin S., Topham, David J., Sangster, Mark Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450111/
https://ncbi.nlm.nih.gov/pubmed/30728266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00169-19
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