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Antigenicity of the 2015–2016 seasonal H1N1 human influenza virus HA and NA proteins

Antigenic drift of the hemagglutinin (HA) and neuraminidase (NA) influenza virus proteins contributes to reduced vaccine efficacy. To analyze antigenic drift in human seasonal H1N1 viruses derived from the 2009 pandemic H1N1 virus (pH1N1-like viruses) accounts for the limited effectiveness (around 4...

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Bibliographic Details
Published in:PLoS One
Main Authors: Clark, Amelia M., DeDiego, Marta L., Anderson, Christopher S., Wang, Jiong, Yang, Hongmei, Nogales, Aitor, Martinez-Sobrido, Luis, Zand, Martin S., Sangster, Mark Y., Topham, David J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690631/
https://ncbi.nlm.nih.gov/pubmed/29145498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188267
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