Monoallelic expression in melanoma

BACKGROUND: Monoallelic expression (MAE) is a frequent genomic phenomenon in normal tissues, however its role in cancer is yet to be fully understood. MAE is defined as the expression of a gene that is restricted to one allele in the presence of a diploid heterozygous genome. Constitutive MAE occurs...

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Veröffentlicht in:J Transl Med
Hauptverfasser: Silcock, Lee, Almabrazi, Hakeem, Mokrab, Younes, Jithesh, Puthen, Al-Hashmi, Muna, James, Nicola, Mathew, Rebecca, Mattei, Valentina, Bedognetti, Davide, Lessi, Francesca, Temanni, Ramzi, Seliger, Barbara, Al-Ali, Rashid, Marincola, Francesco M., Wang, Ena, Tomei, Sara
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449950/
https://ncbi.nlm.nih.gov/pubmed/30953523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1863-x
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