Alcohol consumption increases susceptibility to pneumococcal pneumonia in a humanized murine HIV model mediated by intestinal dysbiosis.

Alcohol use in persons living with HIV (PLWH) worsens the severity of bacterial pneumonia. However, the exact mechanism(s) by which this occurs remain ill-defined. We hypothesized that alcohol in the setting of HIV infection decreases S. pneumoniae clearance from the lung through mechanisms mediated...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Alcohol
Prif Awduron: Samuelson, Derrick R., Siggins, Robert W., Ruan, Sanbao, Amedee, Angela M., Sun, Jiusong, Zhu, Quan Karen, Marasco, Wayne A., Taylor, Christopher M., Luo, Meng, Welsh, David A., Shellito, Judd E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449221/
https://ncbi.nlm.nih.gov/pubmed/30213614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2018.08.012
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