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The Many Talents of TGF-β in the Kidney

PURPOSE OF REVIEW: Pre-clinical data suggests that transforming growth factor-β (TGF-β) is arguably the most potent profibrotic growth factor in kidney injury. Despite this, recent clinical trials targeting TGF-β have been disappointing. These negative studies suggest that TGF-β signaling in the inj...

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Bibliografiske detaljer
Udgivet i:Curr Opin Nephrol Hypertens
Hovedforfatter: Gewin, Leslie
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449206/
https://ncbi.nlm.nih.gov/pubmed/30893214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MNH.0000000000000490
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