PAM50 Molecular Intrinsic Subtypes in the Nurses’ Health Study Cohorts

BACKGROUND: Modified median and subgroup-specific gene centering are two essential pre-processing methods to assign breast cancer molecular subtypes by PAM50. We evaluated the PAM50 subtypes derived from both methods in a subset of Nurses’ Health Study (NHS) and NHSII participants; correlated tumor...

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Veröffentlicht in:Cancer Epidemiol Biomarkers Prev
Hauptverfasser: Kensler, Kevin H., Sankar, Venkat N., Wang, Jun, Zhang, Xuehong, Rubadue, Christopher A., Baker, Gabrielle M., Parker, Joel S., Hoadley, Katherine A., Stancu, Andreea L., Pyle, Michael E., Collins, Laura C., Hunter, David J., Eliassen, A. Heather, Hankinson, Susan E., Tamimi, Rulla M., Heng, Yujing J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449178/
https://ncbi.nlm.nih.gov/pubmed/30591591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-18-0863
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