Bacterial fitness in chronic wounds appears to be mediated by the capacity for high-density growth, not virulence or biofilm functions

While much is known about acute infection pathogenesis, the understanding of chronic infections has lagged. Here we sought to identify the genes and functions that mediate fitness of the pathogen Pseudomonas aeruginosa in chronic wound infections, and to better understand the selective environment i...

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Udgivet i:PLoS Pathog
Main Authors: Morgan, Sarah J., Lippman, Soyeon I., Bautista, Gilbert E., Harrison, Joe J., Harding, Christopher L., Gallagher, Larry A., Cheng, Ann-Chee, Siehnel, Richard, Ravishankar, Sumedha, Usui, Marcia L., Olerud, John E., Fleckman, Philip, Wolcott, Randall D., Manoil, Colin, Singh, Pradeep K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448920/
https://ncbi.nlm.nih.gov/pubmed/30893371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007511
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