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Determinants of Extreme β-Lactam Tolerance in the Burkholderia pseudomallei Complex

Slow-growing bacteria are insensitive to killing by antibiotics, a trait known as antibiotic tolerance. In this study, we characterized the genetic basis of an unusually robust β-lactam (meropenem) tolerance seen in Burkholderia species. We identified tolerance genes under three different slow-growt...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Held, Kiara, Gasper, Joe, Morgan, Sarah, Siehnel, Richard, Singh, Pradeep, Manoil, Colin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913950/
https://ncbi.nlm.nih.gov/pubmed/29439964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00068-18
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