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Pharmacological targeting of mutant p53
TP53 is the most commonly mutated gene in cancer, with over half of all human cancers harboring a mutation in the gene. The p53 protein is a transcription factor that functions as a tumor suppressor, and a subset of its numerous roles include the arrest of proliferation, promotion of DNA repair, and...
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| Publicado no: | Transl Cancer Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6448797/ https://ncbi.nlm.nih.gov/pubmed/30956950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tcr.2016.11.74 |
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