Experimental non-alcoholic steatohepatitis in Göttingen Minipigs: consequences of high fat-fructose-cholesterol diet and diabetes

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in humans, and ranges from steatosis to non-alcoholic steatohepatitis (NASH), the latter with risk of progression to cirrhosis. The Göttingen Minipig has been used in studies of obesity and diabetes, but liver cha...

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Dettagli Bibliografici
Pubblicato in:J Transl Med
Autori principali: Schumacher-Petersen, Camilla, Christoffersen, Berit Østergaard, Kirk, Rikke Kaae, Ludvigsen, Trine Pagh, Zois, Nora Elisabeth, Pedersen, Henrik Duelund, Vyberg, Mogens, Olsen, Lisbeth Høier
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448276/
https://ncbi.nlm.nih.gov/pubmed/30943987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1854-y
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