Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals

BACKGROUND: From a pharmacological perspective, readily-available, well-characterized animal models of cardiovascular disease, including relevant in vivo markers of atherosclerosis are important for evaluation of novel drug candidates. Furthermore, considering the impact of diabetes mellitus on athe...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Ludvigsen, Trine Pagh, Kirk, Rikke Kaae, Christoffersen, Berit Østergaard, Pedersen, Henrik Duelund, Martinussen, Torben, Kildegaard, Jonas, Heegaard, Peter M. H., Lykkesfeldt, Jens, Olsen, Lisbeth Høier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580291/
https://ncbi.nlm.nih.gov/pubmed/26394837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0670-2
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