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Core Outcome Measures in Preclinical Assessment of Candidate Analgesics

All preclinical procedures for analgesic drug discovery involve two components: 1) a “pain stimulus” (the principal independent variable), which is delivered to an experimental subject with the intention of producing a pain state; and 2) a “pain behavior” (the principal dependent variable), which is...

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Библиографические подробности
Опубликовано в: :Pharmacol Rev
Главный автор: Negus, S. Stevens
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448246/
https://ncbi.nlm.nih.gov/pubmed/30898855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/pr.118.017210
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