Integrated Metabolomics and Proteomics Analysis Revealed Second Messenger System Disturbance in Hippocampus of Chronic Social Defeat Stress Rat

Depression is a common and disabling mental disorder characterized by high disability and mortality, but its physiopathology remains unclear. In this study, we combined a non-targeted gas chromatography-mass spectrometry (GC-MS)-based metabolomic approach and isobaric tags for relative and absolute...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Yang, Li-Ning, Pu, Jun-Cai, Liu, Lan-Xiang, Wang, Guo-Wei, Zhou, Xin-Yu, Zhang, Yu-Qing, Liu, Yi-Yun, Xie, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448023/
https://ncbi.nlm.nih.gov/pubmed/30983951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00247
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