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Social defeat stress causes depression-like behavior with metabolite changes in the prefrontal cortex of rats

Major depressive disorder is a serious mental disorder with high morbidity and mortality. The role of social stress in the development of depression remains unclear. Here, we used the social defeat stress paradigm to induce depression-like behavior in rats, then evaluated the behavior of the rats an...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Liu, Yi-Yun, Zhou, Xin-Yu, Yang, Li-Ning, Wang, Hai-Yang, Zhang, Yu-Qing, Pu, Jun-Cai, Liu, Lan-Xiang, Gui, Si-Wen, Zeng, Li, Chen, Jian-Jun, Zhou, Chan-Juan, Xie, Peng
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409051/
https://ncbi.nlm.nih.gov/pubmed/28453574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176725
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