Social defeat stress causes depression-like behavior with metabolite changes in the prefrontal cortex of rats

Major depressive disorder is a serious mental disorder with high morbidity and mortality. The role of social stress in the development of depression remains unclear. Here, we used the social defeat stress paradigm to induce depression-like behavior in rats, then evaluated the behavior of the rats an...

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Vydáno v:PLoS One
Hlavní autoři: Liu, Yi-Yun, Zhou, Xin-Yu, Yang, Li-Ning, Wang, Hai-Yang, Zhang, Yu-Qing, Pu, Jun-Cai, Liu, Lan-Xiang, Gui, Si-Wen, Zeng, Li, Chen, Jian-Jun, Zhou, Chan-Juan, Xie, Peng
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409051/
https://ncbi.nlm.nih.gov/pubmed/28453574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176725
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