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Experimental observation of mitochondrial oxidative damage of liver cells induced by isonicotinic acid hydrazide

The aim of the present study was to investigate the oxidative damage of liver mitochondria as an adverse effect of the anti-tuberculosis drug isonicotinic acid hydrazide (INH). The human hepatoblastoma cell line (HepG2) was exposed to INH at concentrations of 0, 1, 2 or 4 mg/ml for 24, 48, 72 or 96...

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Bibliografiske detaljer
Udgivet i:Exp Ther Med
Main Authors: Zheng, Guoying, Wang, Manman, Ren, Qi, Han, Tiesheng, Li, Yuhong, Sun, Shufeng, Li, Xue, Feng, Fumin
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447889/
https://ncbi.nlm.nih.gov/pubmed/30988801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7417
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