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Experimental observation of mitochondrial oxidative damage of liver cells induced by isonicotinic acid hydrazide

The aim of the present study was to investigate the oxidative damage of liver mitochondria as an adverse effect of the anti-tuberculosis drug isonicotinic acid hydrazide (INH). The human hepatoblastoma cell line (HepG2) was exposed to INH at concentrations of 0, 1, 2 or 4 mg/ml for 24, 48, 72 or 96...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Zheng, Guoying, Wang, Manman, Ren, Qi, Han, Tiesheng, Li, Yuhong, Sun, Shufeng, Li, Xue, Feng, Fumin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447889/
https://ncbi.nlm.nih.gov/pubmed/30988801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7417
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