PACAP-38 and PACAP(6–38) Degranulate Rat Meningeal Mast Cells via the Orphan MrgB(3)-Receptor

Infusion of pituitary adenylate cyclase activating peptide-38 (PACAP-38) provokes migraine attacks in migraineurs and headache in non-migraineurs. Adverse events like long-lasting flushing and heat sensation can be terminated with oral antihistamine treatment, indicating the involvement of mast cell...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Pedersen, Sara Hougaard, la Cour, Sanne Hage, Calloe, Kirstine, Hauser, Frank, Olesen, Jes, Klaerke, Dan Arne, Jansen-Olesen, Inger
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447718/
https://ncbi.nlm.nih.gov/pubmed/30983973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00114
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