SPECIFICATION OF POSITIONAL IDENTITY IN FOREBRAIN ORGANOIDS

Human brain organoids generated with current technologies recapitulate histological features of the human brain, but they lack a reproducible topographic organization. During development, spatial topography is determined by gradients of signaling molecules released from discrete signaling centers. W...

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Udgivet i:Nat Biotechnol
Main Authors: Cederquist, Gustav Y., Asciolla, James J., Tchieu, Jason, Walsh, Ryan M, Cornacchia, Daniela, Resh, Marilyn D., Studer, Lorenz
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447454/
https://ncbi.nlm.nih.gov/pubmed/30936566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0085-3
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