Sorafenib for Advanced and Refractory Desmoid Tumors

BACKGROUND: Desmoid tumors (also referred to as aggressive fibromatosis) are connective tissue neoplasms that can arise in any anatomical location and infiltrate the mesentery, neurovascular structures, and visceral organs. There is no standard of care. METHODS: In this double-blind, phase 3 trial,...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Gounder, Mrinal M., Mahoney, Michelle R., Van Tine, Brian A., Ravi, Vinod, Attia, Steven, Deshpande, Hari A., Gupta, Abha A., Milhem, Mohammed M., Conry, Robert M., Movva, Sujana, Pishvaian, Michael J., Riedel, Richard F., Sabagh, Tarek, Tap, William D., Horvat, Natally, Basch, Ethan, Schwartz, Lawrence H., Maki, Robert G., Agaram, Narasimhan P., Lefkowitz, Robert A., Mazaheri, Yousef, Yamashita, Rikiya, Wright, John J., Dueck, Amylou C., Schwartz, Gary K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447029/
https://ncbi.nlm.nih.gov/pubmed/30575484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1805052
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