The metastasis suppressor NME1 inhibits melanoma cell motility via direct transcriptional induction of the integrin beta-3 gene

Expression of the metastasis suppressor NME1 in melanoma is associated with reduced cellular motility, invasion, and metastasis, but mechanisms underlying these activities are not completely understood. Herein we report a novel mechanism through which NME1 drives formation of large, stable focal adh...

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Bibliographic Details
Published in:Exp Cell Res
Main Authors: Leonard, M. Kathryn, Novak, Marián, Snyder, Devin, Snow, Grace, Pamidimukkala, Nidhi, McCorkle, Joseph R., Yang, Xiuwei H., Kaetzel, David M.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446928/
https://ncbi.nlm.nih.gov/pubmed/30458180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2018.11.010
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