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Early Seizures Prematurely Unsilence Auditory Synapses to Disrupt Thalamocortical Critical Period Plasticity

Heightened neural excitability in infancy and childhood results in increased susceptibility to seizures. Such early-life seizures are associated with language deficits and autism that can result from aberrant development of the auditory cortex. Here, we show that early-life seizures disrupt a critic...

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Foilsithe in:Cell Rep
Main Authors: Sun, Hongyu, Takesian, Anne E., Wang, Ting Ting, Lippman-Bell, Jocelyn J., Hensch, Takao K., Jensen, Frances E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446922/
https://ncbi.nlm.nih.gov/pubmed/29847785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.108
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