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Early-life seizures alter synaptic calcium-permeable AMPA receptor function and plasticity

Calcium (Ca(2+))-mediated() signaling pathways are critical to synaptic plasticity. In adults, the NMDA glutamate receptor (NMDAR) represents a major route for activity-dependent synaptic Ca(2+) entry. However, during neonatal development, when synaptic plasticity is high, many AMPA glutamate recept...

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Publicado en:Mol Cell Neurosci
Main Authors: Lippman-Bell, Jocelyn J., Zhou, Chengwen, Sun, Hongyu, Feske, Joel S., Jensen, Frances E.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056834/
https://ncbi.nlm.nih.gov/pubmed/27521497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2016.08.002
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