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Tcf1 and Lef1 are required for the immunosuppressive function of regulatory T cells
Tcf1 and Lef1 have versatile functions in regulating T cell development and differentiation, but intrinsic requirements for these factors in regulatory T (T reg) cells remain to be unequivocally defined. Specific ablation of Tcf1 and Lef1 in T reg cells resulted in spontaneous multi-organ autoimmuni...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446865/ https://ncbi.nlm.nih.gov/pubmed/30837262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20182010 |
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