YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility

Cell migration initiates by traction generation through reciprocal actomyosin tension and focal adhesion reinforcement, but continued motility requires adaptive cytoskeletal remodeling and adhesion release. Here, we asked whether de novo gene expression contributes to this cytoskeletal feedback. We...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Mason, Devon E., Collins, Joseph M., Dawahare, James H., Nguyen, Trung Dung, Lin, Yang, Voytik-Harbin, Sherry L., Zorlutuna, Pinar, Yoder, Mervin C., Boerckel, Joel D.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446844/
https://ncbi.nlm.nih.gov/pubmed/30737263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201806065
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