Skeletal cell YAP and TAZ combinatorially promote bone development

The functions of the paralogous transcriptional coactivators Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) in bone are controversial. Each has been observed to promote or inhibit osteogenesis in vitro, with reports of both equivalent and divergent function...

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Vydáno v:FASEB J
Hlavní autoři: Kegelman, Christopher D., Mason, Devon E., Dawahare, James H., Horan, Daniel J., Vigil, Genevieve D., Howard, Scott S., Robling, Alexander G., Bellido, Teresita M., Boerckel, Joel D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2018
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901392/
https://ncbi.nlm.nih.gov/pubmed/29401582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700872R
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