Sulfur Dioxide Activates Cl(-)/HCO(3)(-) Exchanger via Sulphenylating AE2 to Reduce Intracellular pH in Vascular Smooth Muscle Cells

Sulfur dioxide (SO(2)) is a colorless and irritating gas. Recent studies indicate that SO(2) acts as the gas signal molecule and inhibits vascular smooth muscle cell (VSMC) proliferation. Cell proliferation depends on intracellular pH (pH(i)). Transmembrane cystein mutation of Na(+)- independent Cl(...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Wang, Yi, Wang, Xiuli, Chen, Selena, Tian, Xiaoyu, Zhang, Lulu, Huang, Yaqian, Tang, Chaoshu, Du, Junbao, Jin, Hongfang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446831/
https://ncbi.nlm.nih.gov/pubmed/30971931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00313
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