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Natural Products in the ‘Marketplace’: Interfacing Synthesis and Biology

Drugs are discovered through the biological screening of collections of compounds, followed by optimization toward functional endpoints. The properties of screening collections are often balanced between diversity, physicochemical favorability, intrinsic complexity and synthetic tractability.(1) Whe...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Huffman, Benjamin J., Shenvi, Ryan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446556/
https://ncbi.nlm.nih.gov/pubmed/30682249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b11297
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