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Natural Products in the ‘Marketplace’: Interfacing Synthesis and Biology
Drugs are discovered through the biological screening of collections of compounds, followed by optimization toward functional endpoints. The properties of screening collections are often balanced between diversity, physicochemical favorability, intrinsic complexity and synthetic tractability.(1) Whe...
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| Pubblicato in: | J Am Chem Soc |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446556/ https://ncbi.nlm.nih.gov/pubmed/30682249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b11297 |
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