Tobacco and Antiretrovirals Modulate Transporter, Metabolic Enzyme, and Antioxidant Enzyme Expression and Function in Polarized Macrophages

BACKGROUND: Cigarette smoking increases systemic oxidative stress, inflammation, and viral replication in individuals with HIV. Macrophages are infected during HIV infection and serve as an important reservoir throughout the process. Macrophages exist in two phenotypes, the classically acti-vated M1...

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Veröffentlicht in:Curr HIV Res
Hauptverfasser: Mu, Ying, Patters, Benjamin J., Midde, Narasimha M., He, Hui, Kumar, Santosh, Cory, Theodore J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Bentham Science Publishers 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446460/
https://ncbi.nlm.nih.gov/pubmed/30706821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570162X17666190130114531
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