Trigeminovascular calcitonin gene-related peptide function in Cacna1a R192Q-mutated knock-in mice

Familial hemiplegic migraine type 1 (FHM1) is a rare migraine subtype. Whereas transgenic knock-in mice with the human pathogenic FHM1 R192Q missense mutation in the Cacna1a gene reveal overall neuronal hyperexcitability, the effects on the trigeminovascular system and calcitonin gene-related peptid...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cereb Blood Flow Metab
Prif Awduron: Chan, Kayi Y, Labastida-Ramírez, Alejandro, Ramírez-Rosas, Martha B, Labruijere, Sieneke, Garrelds, Ingrid M, Danser, Alexander HJ, van den Maagdenberg, Arn MJM, MaassenVanDenBrink, Antoinette
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2017
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446415/
https://ncbi.nlm.nih.gov/pubmed/28792272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17725673
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