The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients With Glioblastoma

Background: Glioblastoma (GBM) is the most aggressive primary brain tumor in adults and is associated with a median overall survival (mOS) of 16–21 months. Our previous work found a negative association between advanced aging and the survival benefit after treatment with immunotherapy in an experime...

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Pubblicato in:Front Pharmacol
Autori principali: Ladomersky, Erik, Scholtens, Denise M., Kocherginsky, Masha, Hibler, Elizabeth A., Bartom, Elizabeth T., Otto-Meyer, Sebastian, Zhai, Lijie, Lauing, Kristen L., Choi, Jaehyuk, Sosman, Jeffrey A., Wu, Jennifer D., Zhang, Bin, Lukas, Rimas V., Wainwright, Derek A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446059/
https://ncbi.nlm.nih.gov/pubmed/30971917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00200
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