Identification of Target Genes at Juvenile Idiopathic Arthritis GWAS Loci in Human Neutrophils

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease among children which could cause severe disability. Genomic studies have discovered substantial number of risk loci for JIA, however, the mechanism of how these loci affect JIA development is not fully understood. Neutr...

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Publicado en:Front Genet
Autores principales: Li, Junyi, Yuan, Xiucheng, March, Michael E., Yao, Xueming, Sun, Yan, Chang, Xiao, Hakonarson, Hakon, Xia, Qianghua, Meng, Xinyi, Li, Jin
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445851/
https://ncbi.nlm.nih.gov/pubmed/30972099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00181
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