Identification of Target Genes at Juvenile Idiopathic Arthritis GWAS Loci in Human Neutrophils

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease among children which could cause severe disability. Genomic studies have discovered substantial number of risk loci for JIA, however, the mechanism of how these loci affect JIA development is not fully understood. Neutr...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Li, Junyi, Yuan, Xiucheng, March, Michael E., Yao, Xueming, Sun, Yan, Chang, Xiao, Hakonarson, Hakon, Xia, Qianghua, Meng, Xinyi, Li, Jin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445851/
https://ncbi.nlm.nih.gov/pubmed/30972099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00181
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