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TiO(2) Photocatalyzed Oxidation of Drugs Studied by Laser Ablation Electrospray Ionization Mass Spectrometry
In drug discovery, it is important to identify phase I metabolic modifications as early as possible to screen for inactivation of drugs and/or activation of prodrugs. As the major class of reactions in phase I metabolism is oxidation reactions, oxidation of drugs with TiO(2) photocatalysis can be us...
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| Veröffentlicht in: | J Am Soc Mass Spectrom |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer US
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6445813/ https://ncbi.nlm.nih.gov/pubmed/30617860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-018-2120-x |
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