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TiO(2) Photocatalyzed Oxidation of Drugs Studied by Laser Ablation Electrospray Ionization Mass Spectrometry

In drug discovery, it is important to identify phase I metabolic modifications as early as possible to screen for inactivation of drugs and/or activation of prodrugs. As the major class of reactions in phase I metabolism is oxidation reactions, oxidation of drugs with TiO(2) photocatalysis can be us...

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Bibliografiske detaljer
Udgivet i:J Am Soc Mass Spectrom
Main Authors: van Geenen, Fred A. M. G., Franssen, Maurice C. R., Miikkulainen, Ville, Ritala, Mikko, Zuilhof, Han, Kostiainen, Risto, Nielen, Michel W. F.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445813/
https://ncbi.nlm.nih.gov/pubmed/30617860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-018-2120-x
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