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Up-regulation of PCSK9 gene expression and diminished level of LDL-receptor in rat liver as a potential cause of post-lipectomy hypercholesterolemia

Studies designed to examine effects of fat mass reduction (including lipodystrophy and lipectomy) on human serum total and LDL-cholesterol concentrations are inconsistent. The purpose of this study was to examine effect of partial lipectomy in rats (as an experimental model of fat mass reduction in...

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Vydáno v:Mol Cell Biochem
Hlavní autoři: Dettlaff-Pokora, Agnieszka, Sucajtys-Szulc, Elzbieta, Sledzinski, Tomasz
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445806/
https://ncbi.nlm.nih.gov/pubmed/30483910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-018-3484-8
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