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Elastography can map the local inverse relationship between shear modulus and drug delivery within the pancreatic ductal adenocarcinoma microenvironment

PURPOSE: High tissue pressure prevents chemotherapeutics from reaching the core of pancreatic tumors. Therefore, targeted therapies have been developed to reduce this pressure. While point probes have shown the effectiveness of these pressure-reducing therapies via single location estimates, ultraso...

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Publicado en:Clin Cancer Res
Autores principales: Wang, Hexuan, Mislati, Reem, Ahmed, Rifat, Vincent, Phuong, Nwabunwanne, Solumtochukwu, Gunn, Jason R., Pogue, Brian W., Doyley, Marvin M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445768/
https://ncbi.nlm.nih.gov/pubmed/30352906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2684
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