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Elastography can map the local inverse relationship between shear modulus and drug delivery within the pancreatic ductal adenocarcinoma microenvironment

PURPOSE: High tissue pressure prevents chemotherapeutics from reaching the core of pancreatic tumors. Therefore, targeted therapies have been developed to reduce this pressure. While point probes have shown the effectiveness of these pressure-reducing therapies via single location estimates, ultraso...

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Dettagli Bibliografici
Pubblicato in:Clin Cancer Res
Autori principali: Wang, Hexuan, Mislati, Reem, Ahmed, Rifat, Vincent, Phuong, Nwabunwanne, Solumtochukwu, Gunn, Jason R., Pogue, Brian W., Doyley, Marvin M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445768/
https://ncbi.nlm.nih.gov/pubmed/30352906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2684
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