Elastography can map the local inverse relationship between shear modulus and drug delivery within the pancreatic ductal adenocarcinoma microenvironment

PURPOSE: High tissue pressure prevents chemotherapeutics from reaching the core of pancreatic tumors. Therefore, targeted therapies have been developed to reduce this pressure. While point probes have shown the effectiveness of these pressure-reducing therapies via single location estimates, ultraso...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Wang, Hexuan, Mislati, Reem, Ahmed, Rifat, Vincent, Phuong, Nwabunwanne, Solumtochukwu, Gunn, Jason R., Pogue, Brian W., Doyley, Marvin M.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445768/
https://ncbi.nlm.nih.gov/pubmed/30352906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-2684
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