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Unraveling the Cellular Mechanism of Assembling Cholesterols for Selective Cancer Cell Death
Acquired drug resistance remains a challenge in chemotherapy. Here we show enzymatic, in-situ assembling of cholesterol derivatives to act as polypharmaceuticals for selectively inducing death of cancer cells via multiple pathways and without inducing acquired drug resistance. A conjugate of tyrosin...
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| Publicado en: | Mol Cancer Res |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6445745/ https://ncbi.nlm.nih.gov/pubmed/30552234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0931 |
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