Enzyme-Instructed Intracellular Molecular Self-assembly to Boost Activity of Cisplatin against Drug-Resistant Ovarian Cancer Cells

Anticancer drug resistance demands innovative approaches that boost the activity of drugs against drug- resistant cancers without increasing the systemic toxicity. Here we show the use of enzyme-instructed self-assembly (EIA) to generate intracellular supramolecular assemblies that drastically boost...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Li, Jie, Kuang, Yi, Shi, Junfeng, Zhou, Jie, Medina, Jamie E., Zhou, Rong, Yuan, Dan, Yang, Cuihong, Wang, Huaimin, Yang, Zhimou, Liu, Jianfeng, Dinulescu, Daniela M., Xu, Bing
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681442/
https://ncbi.nlm.nih.gov/pubmed/26365295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201507157
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