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Ano1 mediates pressure-sensitive contraction frequency changes in mouse lymphatic collecting vessels

Lymphatic collecting vessels exhibit spontaneous contractions with a pressure-dependent contraction frequency. The initiation of contraction has been proposed to be mediated by the activity of a Ca(2+)-activated Cl(−) channel (CaCC). Here, we show that the canonical CaCC Anoctamin 1 (Ano1, TMEM16a)...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Zawieja, Scott D., Castorena, Jorge A., Gui, Peichun, Li, Min, Bulley, Simon A., Jaggar, Jonathan H., Rock, Jason R., Davis, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445586/
https://ncbi.nlm.nih.gov/pubmed/30862712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812294
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