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Cadmium opens GluK2 kainate receptors with cysteine substitutions at the M3 helix bundle crossing

Kainate receptors are ligand-gated ion channels that have two major roles in the central nervous system: they mediate a postsynaptic component of excitatory neurotransmission at some glutamatergic synapses and modulate transmitter release at both excitatory and inhibitory synapses. Accumulating evid...

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Detalles Bibliográficos
Publicado en:J Gen Physiol
Main Authors: Wilding, Timothy J., Huettner, James E.
Formato: Artigo
Idioma:Inglês
Publicado: Rockefeller University Press 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445585/
https://ncbi.nlm.nih.gov/pubmed/30498132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812234
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