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Cadmium opens GluK2 kainate receptors with cysteine substitutions at the M3 helix bundle crossing

Kainate receptors are ligand-gated ion channels that have two major roles in the central nervous system: they mediate a postsynaptic component of excitatory neurotransmission at some glutamatergic synapses and modulate transmitter release at both excitatory and inhibitory synapses. Accumulating evid...

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Détails bibliographiques
Publié dans:J Gen Physiol
Auteurs principaux: Wilding, Timothy J., Huettner, James E.
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445585/
https://ncbi.nlm.nih.gov/pubmed/30498132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812234
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