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The prevalence and antifolate drug resistance profiles of Plasmodium falciparum in study participants randomized to discontinue or continue cotrimoxazole prophylaxis

OBJECTIVE: Cotrimoxazole prevents opportunistic infections including falciparum malaria in HIV-infected individuals but there are concerns of cross-resistance to other antifolate drugs such as sulphadoxine-pyrimethamine (SP). In this study, we investigated the prevalence of antifolate-resistance mut...

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Bibliografische gegevens
Gepubliceerd in:PLoS Negl Trop Dis
Hoofdauteurs: Juma, Dennis W., Muiruri, Peninah, Yuhas, Krista, John-Stewart, Grace, Ottichilo, Ronald, Waitumbi, John, Singa, Benson, Polyak, Christina, Kamau, Edwin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445470/
https://ncbi.nlm.nih.gov/pubmed/30897090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007223
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