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Translating in vivo metabolomic analysis of succinate dehydrogenase deficient tumours into clinical utility

PURPOSE: Mutations in the mitochondrial enzyme succinate dehydrogenase (SDH) subunit genes are associated with a wide spectrum of tumours including phaeochromocytoma and paraganglioma (PPGL) 1, 2, gastrointestinal stromal tumours (GIST) 3, renal cell carcinoma (RCC) 4 and pituitary adenomas5. SDH-re...

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Bibliografische gegevens
Gepubliceerd in:JCO Precis Oncol
Hoofdauteurs: Casey, Ruth T, McLean, Mary A, Madhu, Basetti, Challis, Benjamin. G, ten Hoopen, Rogier., Roberts, Thomas., Clark, Graeme. R., Pittfield, Deborah, Simpson, Helen L, Bulusu, Venkata R, Allinson, Kieran, Happerfield, Lisa, Park, Soo-Mi, Marker, Alison, Giger, Olivier, Maher, Eamonn R, Gallagher, Ferdia A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445359/
https://ncbi.nlm.nih.gov/pubmed/30949620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.17.00191
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