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Translating in vivo metabolomic analysis of succinate dehydrogenase deficient tumours into clinical utility

PURPOSE: Mutations in the mitochondrial enzyme succinate dehydrogenase (SDH) subunit genes are associated with a wide spectrum of tumours including phaeochromocytoma and paraganglioma (PPGL) 1, 2, gastrointestinal stromal tumours (GIST) 3, renal cell carcinoma (RCC) 4 and pituitary adenomas5. SDH-re...

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Bibliografski detalji
Izdano u:JCO Precis Oncol
Glavni autori: Casey, Ruth T, McLean, Mary A, Madhu, Basetti, Challis, Benjamin. G, ten Hoopen, Rogier., Roberts, Thomas., Clark, Graeme. R., Pittfield, Deborah, Simpson, Helen L, Bulusu, Venkata R, Allinson, Kieran, Happerfield, Lisa, Park, Soo-Mi, Marker, Alison, Giger, Olivier, Maher, Eamonn R, Gallagher, Ferdia A
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445359/
https://ncbi.nlm.nih.gov/pubmed/30949620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.17.00191
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